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1

Evolving From Reductionism to Holism

Federoff, Howard J., Gostin, Lawrence O.

Journal:

JAMA The Journal of the American Medical Association

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

2

Temporal and spatial localization of nectin-1 and l-afadin during synaptogenesis in hippocampal neurons

Seung T. Lim, Kuei-Cheng Lim, Rita E. Giuliano, Howard J. Federoff

Journal:

The Journal of Comparative Neurology

Year:

2008

Language:

english

File:

PDF, 2.60 MB

english, 2008

3

Repeated Acquisition and Performance Chamber for Mice: A Paradigm for Assessment of Spatial Learning and Memory

Andrew I. Brooks, Deborah A. Cory-Slechta, Stephanie L. Murg, Howard J. Federoff

Journal:

Neurobiology of Learning and Memory

Year:

2000

Language:

english

File:

PDF, 7.91 MB

english, 2000

4

Gazing into the future: Parkinson's disease gene therapeutics to modify natural history

Kathleen A. Maguire-Zeiss, Timothy R. Mhyre, Howard J. Federoff

Journal:

Experimental Neurology

Year:

2008

Language:

english

File:

PDF, 633 KB

english, 2008

5

Therapeutic potential of vaccines for Alzheimer’s disease

Shah, Salim, Federoff, Howard J

Journal:

Year:

2011

Language:

english

File:

PDF, 538 KB

english, 2011

6

EDITORIAL: TECHNOLOGY, INNOVATION, AND HEALTH

Sanberg, Paul R., Federoff, Howard J.

Journal:

Technology & Innovation

Year:

2012

Language:

english

File:

PDF, 28 KB

english, 2012

7

ANNOUNCING THE INAUGURAL ISSUE OF TECHNOLOGY AND INNOVATION (FORMERLY TECHNOLOGY)

Sanberg, Paul R., Federoff, Howard J.

Journal:

Technology & Innovation

Year:

2010

Language:

english

File:

PDF, 141 KB

english, 2010

8

Development of vaccination approaches for the treatment of neurological diseases

Howard J. Federoff

Journal:

The Journal of Comparative Neurology

Year:

2009

Language:

english

File:

PDF, 2.05 MB

english, 2009

9

Ex vivo hepatic gene transfer in mouse using a defective herpes simplex virus-1 vector

Bing Lu, Sanjeev Gupta, Howard Federoff

Journal:

Year:

1995

Language:

english

File:

PDF, 1.18 MB

english, 1995

10

Rapid and efficient gene transfer in human hepatocytes by herpes viral vectors

Yuman Fong, Howard J. Federoff, Michael Brownlee, David Blumberg, Leslie H. Blumgart, Murray F. Brennan

Journal:

Year:

1995

Language:

english

File:

PDF, 898 KB

english, 1995

11

Hexamethylene bisacetamide leads to reduced helper virus-free HSV-1 amplicon expression titers via suppression of ICP0

Clark A. Burris, Suresh de Silva, Wade C. Narrow, Ann E. Casey, Louis T. Lotta Jr, Howard J. Federoff, William J. Bowers

Journal:

The Journal of Gene Medicine

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

12

Localized gene transfer into organotypic hippocampal slice cultures and acute hippocampal slices

Patrizia Casaccia-Bonnefil, Eirikur Benedikz, Hong Shen, Armin Stelzer, Diane Edelstein, Michael Geschwind, Michael Brownlee, Howard J. Federoff, Peter J. Bergold

Journal:

Journal of Neuroscience Methods

Year:

1993

Language:

english

File:

PDF, 1.05 MB

english, 1993

13

Herpes simplex virus amplicon delivery of a hypoxia-inducible angiogenic inhibitor blocks capillary formation in hepatocellular carcinoma

Richard H. Pin, Maura Reinblatt, William J. Bowers, Howard J. Federoff, Yuman Fong

Journal:

Journal of Gastrointestinal Surgery

Year:

2004

Language:

english

File:

PDF, 271 KB

english, 2004

14

An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies

Deborah A. Ryan, Wade C. Narrow, Howard J. Federoff, William J. Bowers

Journal:

Journal of Neuroscience Methods

Year:

2010

Language:

english

File:

PDF, 706 KB

english, 2010

15

Microarrays in Parkinson’s Disease: A Systematic Approach

Renee M. Miller, Howard J. Federoff

Journal:

Neurotherapeutics

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

16

Somatic gene transfer approaches to manipulate neural networks

Howard J. Federoff, Andrew Brooks, Bashkar Muhkerjee, Timothy Corden

Journal:

Journal of Neuroscience Methods

Year:

1997

Language:

english

File:

PDF, 1.58 MB

english, 1997

17

Reproducible and efficient murine CNS gene delivery using a microprocessor-controlled injector

Andrew I Brooks, Marc W Halterman, Christopher A Chadwick, Beverly L Davidson, Mary Haak-Frendscho, Clyde Radel, Chris Porter, Howard J Federoff

Journal:

Journal of Neuroscience Methods

Year:

1998

Language:

english

File:

PDF, 2.78 MB

english, 1998

18

Luciferase: a sensitive and quantitative probe for blood-brain barrier disruption

Sophie X Deng, Nariman Panahian, Harold James, Harris A Gelbard, Howard J Federoff, Stephen Dewhurst, Leon G Epstein

Journal:

Journal of Neuroscience Methods

Year:

1998

Language:

english

File:

PDF, 237 KB

english, 1998

19

Effective treatment of pancreatic tumors with two multimutated herpes simplex oncolytic viruses

Priscilla F. McAuliffe, William R. Jarnagin, Paul Johnson, Keith A. Delman, Howard Federoff, Yuman Fong

Journal:

Journal of Gastrointestinal Surgery

Year:

2000

Language:

english

File:

PDF, 628 KB

english, 2000

20

G207, modified herpes simplex virus type 1, kills human pancreatic cancer cells in vitro

Jonathan H. Lee, Howard J. Federoff, Luke O. Schoeniger

Journal:

Journal of Gastrointestinal Surgery

Year:

1999

Language:

english

File:

PDF, 540 KB

english, 1999

21

Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer

Joseph J. Bennett, David A. Kooby, Keith Delman, Priscilla McAuliffe, Marc W. Halterman, Howard Federoff, Yuman Fong

Journal:

Journal of Molecular Medicine

Year:

2000

Language:

english

File:

PDF, 146 KB

english, 2000

22

Augmentation of anti-tumor responses of adoptively transferred CD8+T cells in the lymphopenic setting by HSV amplicon transduction

Hovav Nechushtan, Dien Pham, Yu Zhang, Daniel Morgensztern, Kyung H. Yi, Seung-Uon Shin, Howard J. Federoff, William J. Bowers, Khaled A. Tolba, Joseph D. Rosenblatt

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 649 KB

english, 2008

23

In vivo interleukin-2 gene therapy of established tumors with herpes simplex amplicon vectors

Michael D'Angelica, Howard Karpoff, Marc Halterman, Jennifer Ellis, David Klimstra, Diane Edelstein, Michael Brownlee, Howard Federoff, Yuman Fong

Journal:

Cancer Immunology, Immunotherapy

Year:

1999

Language:

english

File:

PDF, 121 KB

english, 1999

24

Future directions for immune modulation in neurodegenerative disorders: focus on Parkinson’s disease

Kathleen A. Maguire-Zeiss, Howard J. Federoff

Journal:

Journal of Neural Transmission

Year:

2010

Language:

english

File:

PDF, 277 KB

english, 2010

25

Immune-Directed Gene Therapeutic Development for Alzheimer’s, Prion, and Parkinson’s Diseases

Maguire-Zeiss, Kathleen A., Federoff, Howard J.

Journal:

Journal of Neuroimmune Pharmacology

Year:

2009

Language:

english

File:

PDF, 296 KB

english, 2009

26

Mutant α-Synuclein Overexpression Mediates Early Proinflammatory Activity

Xiaomin Su, Howard J. Federoff, Kathleen A. Maguire-Zeiss

Journal:

Neurotoxicity Research

Year:

2009

Language:

english

File:

PDF, 615 KB

english, 2009

27

Nur(R1)turing a Notion on the Etiopathogenesis of Parkinson’s Disease

Howard J. Federoff

Journal:

Neurotoxicity Research

Year:

2009

Language:

english

File:

PDF, 504 KB

english, 2009

28

Systems Biology: A Primer

Howard J. Federoff, Timothy R. Mhyre

Journal:

Neurotherapeutics

Year:

2006

Language:

english

File:

PDF, 38 KB

english, 2006

29

Topical Application of Viral Vectors for Epidermal Gene Transfer.

Lu, Bo, Federoff, Howard J., Wang, Yibin, Goldsmith, Lowell A., Scott, Glynis

Journal:

The Journal of Investigative Dermatology

Year:

1997

File:

PDF, 2.45 MB

1997

30

Cloning and Characterization of the Rat Gene Encoding GAP-43

Ed Grabczyk, Mauricio X. Zuber, Howard J. Federoff, Shi-Chung Ng, Alison Pack, Mark C. Fishman

Journal:

European Journal of Neuroscience

Year:

1990

Language:

english

File:

PDF, 932 KB

english, 1990

31

α-Synuclein mediates alterations in membrane conductance: a potential role for α-synuclein oligomers in cell vulnerability

Li Rebekah Feng, Howard J. Federoff, Stefano Vicini, Kathleen A. Maguire-Zeiss

Journal:

European Journal of Neuroscience

Year:

2010

Language:

english

File:

PDF, 270 KB

english, 2010

32

Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional ‘detour’ in the hemisected spinal cord

Lisa Schnell, Arsen S. Hunanyan, William J. Bowers, Philip J. Horner, Howard J. Federoff, Miriam Gullo, Martin E. Schwab, Lorne M. Mendell, Victor L. Arvanian

Journal:

European Journal of Neuroscience

Year:

2011

Language:

english

File:

PDF, 962 KB

english, 2011

33

Characterization of nectin processing mediated by presenilin-dependent gamma-secretase

Jinsook Kim, Allison Chang, Amanda Dudak, Howard J. Federoff, Seung T. Lim

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 462 KB

english, 2011

34

Ectodomain shedding of nectin-1 regulates the maintenance of dendritic spine density

Seung T. Lim, Allison Chang, Rita E. Giuliano, Howard J. Federoff

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 529 KB

english, 2012

35

Gene Therapy in the Inner Ear: Mechanisms and Clinical Implications

THOMAS R. VAN DE WATER, HINRICH STAECKER, MARC W. HALTERMAN, HOWARD J. FEDEROFF

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 918 KB

english, 1999

36

Preface

Howard J. Federoff

Journal:

Annals of the New York Academy of Sciences

Year:

2003

Language:

english

File:

PDF, 80 KB

english, 2003

37

Convergent Pathobiologic Model of Parkinson's Disease

KATHLEEN A. MAGUIRE-ZEISS, HOWARD J. FEDEROFF

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 5.48 MB

2003

38

Development of Nurr1 Stable Cell Lines for the Identification of Downstream Targets

YU LUO, LEIGH A. HENRICKSEN, KATHLEEN A. MAGUIRE-ZEISS, HOWARD J. FEDEROFF

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 1.21 MB

2003

39

10.1038/35065091

Jackson, Mandy, Song, Wei, Liu, Mu-Ya, Jin, Lin, Dykes-Hoberg, Margaret, Lin, Chien-liang G., Bowers, William J., Federoff, Howard J., Sternweis, Paul C., Rothstein, Jeffrey D.

Journal:

Year:

2001

Language:

english

File:

PDF, 292 KB

english, 2001

40

10.1038/89991

Bennett, Joseph J, Tjuvajev, Juri, Johnson, Paul, Doubrovin, Mikhail, Akhurst, Timothy, Malholtra, Sandeep, Hackman, Trevor, Balatoni, Julius, Finn, Ronald, Larson, Steven M, Federoff, Howard, Blasber

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 1.86 MB

english, 2001

41

Nerve growth factor somatic mosaicism produced by herpes virus-directed expression of ere recombinase

Brooks, Andrew I., Muhkerjee, Bhaskar, Panahian, Nariman, Cory-Slechta, Deborah, Federoff, Howard J.

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 1.18 MB

1997

42

Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease

Lee, Byoung Dae, Shin, Joo-Ho, VanKampen, Jackalina, Petrucelli, Leonard, West, Andrew B, Ko, Han Seok, Lee, Yun-Il, Maguire-Zeiss, Kathleen A, Bowers, William J, Federoff, Howard J

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 627 KB

english, 2010

43

Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing

Snyder, Jennifer E., Bowers, William J., Livingstone, Alexandra M., Lee, F. Eun-Hyung, Federoff, Howard J., Mosmann, Tim R.

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 204 KB

english, 2003

44

Efficient cotransduction of tumors by multiple herpes simplex vectors: Implications for tumor vaccine production

Karpoff, Howard M, Kooby, David, D’Angelica, Michael, Mack, Jonathan, Presky, David H, Brownlee, Michael D, Federoff, Howard, Fong, Yuman

Journal:

Cancer Gene Therapy

Year:

2000

Language:

english

File:

PDF, 164 KB

english, 2000

45

Comparison of safety, delivery, and efficacy of two oncolytic herpes viruses (G207 and NV1020) for peritoneal cancer

Mariotti, Adam, Malhotra, Sandeep, Zager, Jonathan, Petrowsky, Henrik, Mastorides, Stephen, Federoff, Howard, Fong, Yuman, Bennett, Joseph J, Delman, Keith A, Burt, Bryan M

Journal:

Cancer Gene Therapy

Year:

2002

Language:

english

File:

PDF, 764 KB

english, 2002

46

Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers

Bowers, W J, Howard, D F, Brooks, A I, Halterman, M W, Federoff, H J

Journal:

Year:

2001

Language:

english

File:

PDF, 402 KB

english, 2001

47

Effects of ex vivo transduction of mesencephalic reaggregates with bcl-2 on grafted dopamine neuron survival

Caryl E. Sortwell, William J. Bowers, Scott E. Counts, Mark R. Pitzer, Matthew F. Fleming, Susan O. McGuire, Kathleen A. Maguire-Zeiss, Howard J. Federoff, Timothy J. Collier

Journal:

Year:

2007

Language:

english

File:

PDF, 1.46 MB

english, 2007

48

Alterations in striatal dopamine catabolism precede loss of substantia nigra neurons in a mouse model of juvenile neuronal ceroid lipofuscinosis

Jill M. Weimer, Jared W. Benedict, Yasser M. Elshatory, Douglas W. Short, Denia Ramirez-Montealegre, Deborah A. Ryan, Noreen A. Alexander, Howard J. Federoff, Jonathan D. Cooper, David A. Pearce

Journal:

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

49

Expression pattern of NuIP gene in adult mouse brain

Yu Luo, Sara Arezou Sarabi, Cristina Backman, Lufei Shan, Barry Hoffer, Howard Federoff

Journal:

Year:

2009

Language:

english

File:

PDF, 3.71 MB

english, 2009

50

Drug discovery dilemma and Cura Quartet collaboration

Salim Shah, Howard J. Federoff

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 232 KB

english, 2009